Both common and rare variants contribute to the genetic architecture of pulmonary fibrosis. Genome-wide association studies have identified common variants, or those with a minor allele frequency of ...

Background Hospitalisation due to acute exacerbations of COPD (AECOPD) is common, and subsequent mortality high. The DECAF score was derived for accurate prediction of mortality and risk ...

Surgical repair of tricuspid atresia has been carried out in three patients; two of these operations have been successful. A new surgical procedure has been used which transmits the whole vena caval ...

Background Indwelling pleural catheters are an effective treatment option for patients with malignant pleural effusions. Despite their popularity, there remains a paucity of data on the patient ...

Background The Clinical COPD Questionnaire (CCQ) is a simple 10-item, health-related quality of life questionnaire (HRQoL) with good psychometric properties. However, little data exists regarding the ...

BACKGROUND The Chronic Respiratory Questionnaire (CRQ) is an established measure of health status for chronic obstructive pulmonary disease (COPD). It has been found to be reproducible and sensitive ...

BACKGROUND The guidelines on chemotherapy and management of tuberculosis in the United Kingdom have been reviewed and updated. METHODS A subcommittee was appointed by the Joint Tuberculosis Committee ...

The acute respiratory distress syndrome (ARDS) is characterised by pulmonary inflammation and increased pulmonary vascular permeability, which results in non-cardiogenic pulmonary oedema and ...

Abstract These guidelines have been replaced by 2010 Guideline On Radical Management Of Patients With Lung Cancer and NICE Lung Cancer Guideline CG121 2011 Superseded By 2010 Guideline On Radical ...

Background: The effect of delay on survival in lung cancer remains uncertain. It is suggested that prompt management of non-small cell lung cancer (NSCLC) can influence prognosis. This study was ...

BACKGROUND The aim of this study was to determine the relationship of the power and recovery stroke of respiratory cilia using digital high speed video imaging. Beat frequency measurements made using ...

Colds caused by respiratory viruses can trigger exacerbations of chronic obstructive pulmonary disease (COPD). This Japanese study investigated whether lansoprazole reduces the frequency of COPD ...