A 43-year-old woman with bipolar disorder and advanced HIV infection was admitted to this hospital because of depressed mood, ...

Digital tobacco-cessation treatments hold great promise. But dedicated efforts will be required to promote access to and ...

Genetic deficiency of otoferlin, a protein critical to synaptic transmission by the sensory hair cells of the ear, causes congenital deafness. Medicines to treat the condition are lacking; ...

The financial assistance policies of some U.S. hospitals now define medical necessity much more restrictively than it has conventionally been understood, as covering only services that are urgently ...

Much diagnostic error is caused by cognitive bias. More than 100 biases affecting clinical decision making have been described, and many medical disciplines ...

In the face of Israel’s ongoing assault on Gaza’s health system and the catastrophic famine caused by the devastation, U.S. physicians have an ethical obligation to respond and support immediate ...

To the Editor: The report by Ye et al. (July 31 issue)1 on the restoration of T-cell receptor signaling in squamous-cell carcinoma (SCC) challenges the so-called hit-and-run model of the role of β- ...

Big data, we have all heard, promise to transform health care. But in the “hype cycle” of emerging technologies, machine learning now rides atop the “peak of inflated expectations,” and we need to ...

Lawmakers and regulators have grown alarmed about vertical integration and the role of “middlemen” in the U.S. health care system. Yet pharmaceutical wholesalers have largely evaded public scrutiny.

Case 28-2025: A 36-Year-Old Man with Abdominal Pain, Fever, and Hypoxemia. G. Dhaliwal and Others. Editorial. Aldosterone Synthase Inhibition for Hypertension ...

Explore this issue of The New England Journal of Medicine (Vol. 392 No. 21).