RMD Open

Potential stratification of TAFRO syndrome by anti-SS-A antibodies status and therapeutic response to rituximab

Objectives Thrombocytopaenia, anasarca, fever, reticulin fibrosis, renal dysfunction and organomegaly (TAFRO) syndrome has ...
RMD Open

HLA-DR risk variants in rheumatoid arthritis: what we know and still do not know

Rheumatoid arthritis (RA) susceptibility is strongly influenced by genetic variations within the major histocompatibility ...
rmdopen.bmj

Accrual of thromboembolic events and antiphospholipid syndrome in new-onset systemic lupus erythematosus: a population-based inception cohort study

Objective This population-based study aimed to determine timing and incidence of arterial and venous thromboembolic events (TE) and antiphospholipid syndrome (APS) relative to systemic lupus ...
rmdopen.bmj

CAR-T cell therapy for treatment-refractory rheumatic autoimmune diseases: a systematic review of clinical outcomes and safety profiles

Objectives Current therapeutic paradigms for treatment-refractory rheumatic diseases rely on chronic immunosuppression with variable efficacy and potential for cumulative toxicity. We systematically ...
rmdopen.bmj

Rheumatoid arthritis, disease-modifying antirheumatic drugs and risk of major osteoporotic fracture: prospective data from the HUNT Study, Norway

Objectives Rheumatoid arthritis has been associated with increased fracture risk. New treatments have improved the course of the disease substantially, but it is not clear if this influences fracture ...
rmdopen.bmj

Correction: Which definitions for MRI sacroiliac joint lesions predict the diagnosis of early axial spondyloarthritis best? A 2-year follow-up in the SPACE cohort

This article has been updated since it was first published online. The numbering of quadrants 3 and 4 in figure 1 was not fully aligned with standard radiological convention for mirrored sacroiliac ...
rmdopen.bmj

Evaluating the efficacy of biologics with and without methotrexate in the treatment of psoriatic arthritis: a network meta-analysis

Introduction An important consideration in the treatment of patients with psoriatic arthritis (PsA) is whether the addition of methotrexate (MTX) to biologics has greater efficacy than biologic ...
rmdopen.bmj

Predictive value of autoantibodies from anti-CCP2, anti-MCV and anti-human citrullinated fibrinogen tests, in early rheumatoid arthritis patients with rapid radiographic ...

Objectives We compared the ability of antibodies against cyclic citrullinated peptides (anti-CCP2), against mutated citrullinated vimentin (anti-MCV) and against citrullinated fibrinogen (AhFibA) to ...
rmdopen.bmj

Sustained remission following the discontinuation of tofacitinib in patients with rheumatoid arthritis (XANADU study): an open-label randomised study

Objective To investigate sustained remission following the discontinuation of tofacitinib in patients with rheumatoid arthritis. Methods Patients who had an inadequate response to methotrexate (MTX) ...
rmdopen.bmj

Persistence of power Doppler ultrasonography-detected synovitis over 1 year of follow-up predicts poor prognosis in rheumatoid arthritis in clinical remission: the SONORE ...

Objectives (1) To assess the progression of ultrasonography-detected synovitis in a cohort of patients with rheumatoid arthritis (RA) in remission during 1 year of follow-up (2) to evaluate the ...
rmdopen.bmj

Anti-dsDNA IgE: a potential non-invasive test for prediction of lupus nephritis relapse

Objectives Discontinuation or continuation of maintenance immunosuppressive therapy (MIST) after a severe lupus nephritis (LN) requires measuring the risk of relapse but reliable clinical and ...