Tau proteins play an important role in our normal brain function, mainly by helping to stabilize neurons in the brain. But in Alzheimer’s disease, tau proteins can misfold and tangle inside neurons.

Tau proteins act like the brain's maintenance crew, helping maintain the structure and proper function of brain cells. In ...

In the spirit of the popular “get organized” new year’s resolution, scientists at Baylor College of Medicine have discovered a new way to declutter brain proteins for 2023. Working for the Jan and Dan ...

This news may put some minds at ease. “Our test identifies very early stages of tau tangle formation — up to a decade before any tau clumps can show up on a brain scan,” said senior study author ...

In the quest to cure Alzheimer’s, the protein known as beta-amyloid has long taken center stage, driving development of a long list of drugs aimed at breaking up “amyloid plaques” in the brain. But ...

An experimental drug can reduce the toxic changes in tau proteins known to damage neurons in brains with Alzheimer’s disease, researchers from Yale School of Medicine and Johns Hopkins University ...

A biomarker test identified tau pathology in Alzheimer's disease before fibrillary tangles developed. Neurofibrillary tangle formation can be prevented by targeting intermediate soluble tau assemblies ...

Researchers have found that when used on monkeys, an experimental drug slowed the process that leads the tau protein to aggregate into neuron-damaging tangles commonly seen in Alzheimer’s disease and ...

Why do memories falter with age? In a preprint posted on bioRxiv on May 22, scientists led by Omer Sharon and sleep researcher Matthew Walker at the University of California, Berkeley, suggested that ...

Tau proteins play an important role in Alzheimer's disease. Tau helps to stabilize neurons in the brain, but in Alzheimer's disease, tau proteins can misfold and tangle inside neurons. These tangles ...