Researchers found that lowering MHC I can expose cancerous or foreign cells to CD4+ T cell attack, reshaping assumptions ...

Researchers at VIB, Ghent University, and VUB have uncovered how two proteins essential for immune cell development work ...

UCLA researchers gave T cells a protected supply of sugar, allowing them to attack solid tumors more effectively.

The cost of CAR T-cell therapy means that the highly effective cancer treatment is unavailable in many parts of the world.

Researchers from the Icahn School of Medicine at Mount Sinai have discovered a promising new way to improve CAR-T cell ...

CAR T-cell therapy is considered a milestone in personalized cancer treatment. In this approach, a patient's own immune cells are genetically modified to recognize and destroy tumor cells. While it ...

CD7 is an attractive target for chimeric antigen receptor (CAR) T-cell therapy in relapsed or refractory T-cell acute lymphoblastic leukemia (ALL). Supportive results of first-in-human studies of base ...

A study led by researchers at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) has identified a mitochondrial ...

Persistent viral infections pose a unique challenge to the immune system. Prolonged antigen exposure drives T cells into a state of exhaustion — a ...

For the past 15 years or so, a class of drugs called immune checkpoint inhibitors have been used to treat melanoma – the most ...