Escherichia coli remains a paradigm for understanding cellular signalling, with its chemotaxis system providing insights into how simple organisms navigate complex environments. At the core of this ...

cases an external molecule dramatically affects cellular function. Our goal in studying any of these processes is the same: a molecule-by-molecule accounting of information transfer in biological ...

Signal transduction by GRB2 and SOS1. When some substances bind to a membrane receptor, a reaction occurs between the receptor and GRB2, which then goes on to bind and activate SOS1. SOS1 can then ...

Bacterial chemotaxis is a sophisticated behavioural process that enables microorganisms to navigate toward favourable environments by detecting subtle differences in chemical gradients. At the heart ...