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Triggering RNA activation on demand: Strategy expands options for therapeutics and gene editing
National University of Singapore (NUS) researchers have devised a method to safely and temporarily "switch off" and then "turn on" ribonucleic acid (RNA) inside cells. This is achieved using ...
Researchers discover how ribosomes contribute to the recognition and removal of RNA crosslinking damage. Aldehydes are toxic compounds that are produced in the body by metabolic processes, especially ...
LONDON--(BUSINESS WIRE)--MiNA Therapeutics Limited, the pioneer in small activating RNA (RNAa) therapeutics, highlights preclinical research presented by academic partners at the annual meeting of the ...
Researchers uncovered how cells coordinate genetic compensation when faulty mRNA is degraded. Small RNA fragments act as sequence “addresses” that recruit ILF3 to activate related backup genes.
A proposed function of TADs is to contribute to gene regulation by promoting chromatin interactions within a TAD and by suppressing interactions between TADs. Here, we directly probe the ...
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Study reveals poxvirus's unique DNA clamp for gene activation
A research team at the University of Würzburg has deciphered another aspect of poxviral gene activation. The study reveals a ...
Although there are striking differences between the cells that make up your eyes, kidneys, brain and toes, the DNA blueprint ...
The glucocorticoid receptor (GR) is a ligand-activated transcription factor that regulates a suite of genes through direct binding of GR to specific DNA promoter elements. GR also interacts with RNA, ...
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