EMG demonstrated profuse true myotonic discharges in every muscle that was tested, with normal motor unit potential morphology and normal conduction velocity. The initial misdiagnosis of ALS resulted ...
Background A 56-year-old woman was referred to a neurogenetic clinic with a history of stiffness and transient weakness. A previous needle electromyogram had confirmed the presence of myotonia, but a ...
Previously, we identified the 8 nt at the 5′ end of exon 7A as an exonic splicing enhancer (ESE) essential for basal inclusion of the exon 29. Given that both −10–15 and 1–25 PS2OMe covered the ESE ...
Sudden death can occur as a consequence of cardiac-conduction abnormalities in the neuromuscular disease myotonic dystrophy type 1. The determinants of the risk of sudden death remain imprecise. We ...
Myotonic dystrophy type 1 incurs high healthcare costs, driven by age and comorbidities like cardiac and respiratory issues. Early detection and integrated management of multisystemic complications ...
Electromyography (EMG) is a diagnostic test that measures how well the muscles respond to the electrical signals emitted to specialized nerve cells called motor nerves. EMG tests are safe and pose ...