NATIONAL HARBOR, MD — Opioid-induced hyperalgesia is among the most pressing concerns in the national discussion of opioid addiction, underscored by the US Food and Drug Administration's (FDA) call ...

LAS VEGAS — Patients with chronic pain being treated with opioids can commonly be expected to develop tolerances to the drug with longer-term treatment, but the emergence of certain, uniquely ...

Morphine and other opioids are vital to treat severe and chronic pain. However, they have two problems - prolonged use creates morphine tolerance, where ever-increasing doses are needed for the same ...

Efficacy and tolerability of oxycodone for oxaliplatin-induced peripheral neuropathy and the extension of folfox therapy in colorectal cancer patients. This is an ASCO Meeting Abstract from the 2014 ...

Pain is the most common reason for which people seek medical attention. Generally opioids are prescribed for the management of pain. However, chronic pain can persist or worsen despite aggressive ...

Research has shown that chronic sleep disruption (CSD) promotes pain, also known as hyperalgesia, which can commonly be experienced as headaches or body pain after a night of poor sleep. However, the ...

Emerging research reveals that people with substance use disorders (SUDs) may have increased pain sensitivity/hyperalgesia when withdrawing from addictive substances ...

Neuropeptide FF receptor 1 (NPFFR1) and NPFFR2 regulate several biological functions and there is a lack of blockers for these receptors that allow the study of their function. Université de ...

Pain responses are triggered in response to physical injury as well as psychological or emotional stressors. However, the mechanisms underlying social or emotional pain transmission are poorly ...

A recent study examining pain among cannabis users suggests that -- unlike long-term opioid use -- regular cannabis use does not appear to increase pain sensitivity. A recent study examining pain ...