DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes. Among them, DNA–histone cross-links (DHCs) occur frequently within ...

If all the DNA in a human cell was stretched out end to end, it would be roughly six feet long. That’s a lot of genetic information to pack into a cell that is, on average, one-fifth the size of a ...

This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...

DNA strands wrap around histones, which are clustered into eight-histone balls that are threaded like beads on a string into fibers that are further intertwined to form chromosomes. Cells don’t store ...

DNA inside the nucleus is not packed as a rigid regular fiber—linker histone H1 dynamically binds and loosely "glues" ...

Antibiotics have saved millions of lives from infectious diseases and are considered one of the most important discoveries of the 20th century. However, as the use (and abuse) of antibiotics has ...