No gene acts alone: interacting variants and protein partnerships can worsen, mask or even rescue disease risk, demanding ...

More than 9 out of 10 Alzheimer's cases could be driven by specific variations in a single gene and the protein it produces, ...

The FDA granted fast track status to VectorY’s VTx-002, an antibody gene therapy targeting TDP-43 protein aggregates in ALS.

Precision and timing of gene expression is essential for normal biological functions and, when disrupted, can lead to many ...

Sometimes, in genetics, two wrongs do make a right. A research team has recently shown that two harmful genetic variants, ...

A new LUMC study has changed our understanding of how cells work. Researchers have discovered that the CFAP20 protein acts as ...

The first patient has been dosed in a Phase 2 clinical trial testing RAG-17 in people with ALS who carry mutations in the ...

UCSF scientists engineered old fibroblast cells to turn their genes on and off in the same way as young fibroblasts. The old ...

The functioning of neurons, cells that transmit information in the nervous system, heavily relies on the production of ...