An important chemical messenger that typically inhibits brain activity might sometimes do the opposite, according to new Yale ...

Depression is a complex condition correlated with multiple differences in brain function and mechanisms. A new study spanning known data about the neurotransmitter GABA and its principal receptors ...

Many people experience temporary cognitive impairment immediately after surgery. In people over age 60, however, about 1 in ...

F. Hoffmann-La Roche Ltd. and Hoffmann-La Roche Inc. have prepared and tested cyclopenta-thieno-diazepine derivatives acting as GABA-A receptor subunit α2β2γ1 positive allosteric modulators (PAMs). As ...

Learn about the five types of substance abuse disorders, how each affects the brain and behavior, and where to get structured ...

Certain proteins found in the human brain have long been known to be critical to controlling how brain cells communicate with each other. So-called GABA A receptors are proteins that control the flow ...

Specific protein receptors in the brain play a vital role in how neurons slow down or stop firing, making them targets for many disorders. Researchers have now constructed a detailed structural map of ...

A simple explanation of how alcohol interacts with GABA receptors in the brain, which can contribute to feelings of ...