When mammalian cells die, they do not simply dissolve away. Instead, they are actively deconstructed and destroyed in defined and organized ways by various regulated cell-death mechanisms. One of ...

Changes in cellular metabolites have been shown to regulate embryonic stem cell development at the earliest stages of life. Metabolites are simple compounds generated during life-sustaining chemical ...

Scientists discovered that the first 100 base pairs of human genes are unusually prone to mutations, especially during the ...

In addition to endodermal and mesodermal cells, alcohol causes changes in DNA methylation in ectodermal cells (in blue), from which the nervous system and brain develop. During the tightly regulated ...

Researchers from the A*STAR Institute of Molecular and Cell Biology (IMCB) have identified Nr1h2, a critical transcription factor essential for early embryo development. Published in Nature ...

Scientists at EPFL have created a scalable 3D organoid model that captures key features of early limb development, revealing ...

Scientists have discovered a method of helping human stem cells thrive in an animal embryo—a key development in efforts to ...

Scientists found that embryonic skin cells “whisper” through faint mechanical tugs, using the same force-sensing proteins that make our ears ultrasensitive. By syncing these micro-movements, the cells ...