Researchers at The Institute of Cancer Research, London identified the CIP2A–TOPBP1 complex as a master regulator of DNA repair during mitosis, coordinating backup pathways that protect chromosomes ...

As the cell proceeds through the stages of cell division (from left to right: interphase, prometaphase, metaphase, and anaphase), chromosomes become progressively more compact through a combination of ...

If measured from beginning to end, the DNA in our cells is too long to fit into the cell’s nucleus, explaining why it must be constantly folded and packaged. When it is time for cell division, and the ...

The human genome has to be carefully organized so it will fit inside of the nuclei of cells, while also remaining accessible ...

Human disease including cancer arises from disfunction of essential processes within a cell. One essential cellular process is the copying of the genomic DNA—the road map of cells—followed by ...

Cell division is an essential process for all life on Earth, yet the exact mechanisms by which cells divide during early ...

Researchers at The University of Hong Kong (HKU) have made an exciting discovery about how human cells protect DNA during cell division, offering new insights into combating diseases such as cancer.

Scientists have recently been learning more about the importance of small bits of circular genetic material known as extrachromosomal DNA (ecDNA). These little circles of DNA can hitch a ride with ...

Researchers have found that the way DNA is packaged in cells can directly impact how fast DNA itself is copied during cell division. They discovered that DNA packaging sends signals through an unusual ...

Many cellular functions in the human body are controlled by biological droplets called Liquid-Liquid Phase Separation (LLPS) droplets. These droplets, made of soft biological materials, exist inside ...

A time-delay circuit enables precise control over the division of synthetic DNA droplets, which mimic biological Liquid-Liquid Phase Separation (LLPS) droplets found in cells. By utilizing a ...