Cadherin-17, also called liver-intestine cadherin, is a calcium-dependent transmembrane glycoprotein that mediates cell–cell adhesion in intestinal epithelium. Expression of cadherin-17 was reported ...

Cadherins are Ca2+ dependent cell-cell adhesion molecules that mediate adhesion between cells and tissues in organisms. They are differentiated into several types based on their location and ...

Fruit-fly ovaries were used in a new study to uncover how E-cadherin guides collective cell migration. According to traditional scientific dogma, E-cadherin acts like the mortar between bricks, ...

E-cadherin, a member of the cadherin family, has a very important role in organizing the epithelium. Most cancers arise from epithelial tissue, and in those cancers, cell adhesion mediated by ...

Preliminary results from a first-in-human phase 1 dose escalation trial of ADRX-0706, a next generation Nectin-4 ADC, in subjects with advanced solid tumors. Safety and efficacy data of study ...

Northeastern University scientists have discovered that a protein in the human brain could potentially be used to grow new neurons in the lab and enhance brain processes affected by aging or ...

Researchers have comprehensively described the network of proteins involved in cell-cell adhesions, or the cadherin interactome. Many biological processes depend on the ability of cells to stick to ...

P-cadherin is a protein commonly found on malignant cancer cells and has been used as a target for antibody-based cancer treatments. UC Davis biomedical engineers have discovered that when an antibody ...

The paper A. Sing et al., “The atypical cadherin Fat directly regulates mitochondrial function and metabolic state,” Cell, 158:1293-1308, 2014. When clustered together in tissues, cells sense and ...

A new study from researchers at the University of Illinois Chicago reveals how the blood-brain barrier gets leakier with age, contributing to memory deficits. The study, published in Cell Reports, ...