Angel Martinez and Jose Ramirez hit back-to-back home runs in the first inning in support of right-hander Slade Cecconi, who recorded a career-high nine strikeouts to lead the Cleveland Guardians to a 4-2 win over the host Houston Astros on Wednesday and a three-game series sweep.

Victor Caratini's two-out homer in the bottom of the inning drew the Astros within a run, but they got no closer. David Fry added a two-out solo homer off Kaleb Ort in the ninth for the final margin.